Tadalafil is an FDA approved drug to treat erectile dysfunction, the condition where a man cannot get an erection and has problems getting or keeping an erection. Tadalafil, which is most commonly sold under the brand name Cialis, works by increasing the amount of blood flowing into certain parts of the body.

It is one of the PDE5 inhibitors, which is a class of medications that work by blocking the enzyme phosphodiesterase type 5. This is the enzyme that normally breaks down cGMP, which is a signal to relax the muscles that make the penis hard. When the enzyme is blocked, more cGMP remains in the cells, causing more relaxation.

Why is Tadalafil Prescribed?

Tadalafil (Cialis) is a medication used to treat erectile dysfunction (ED, impotence) and the symptoms of benign prostatic hyperplasia (BPH) which include difficulty urinating, painful urination, and urinary frequency and urgency in adult men.

How Should Tadalafil Be Used?

How to use Tadalafil

Tadalafil is the active ingredient in Cialis and other medications used to treat ED (erectile dysfunction. Follow your doctor’s instructions on how to use tadalafil and in what dosages you should take it.

Tadalafil can be taken in two different ways: either on a daily basis or on an as-needed basis. Consult with your doctor about your treatment options. 

Tadalafil is sometimes taken as needed, usually at least 30 minutes before sexual activity and no more than once every 24 hours, depending on the individual. Tadalafil is a commonly prescribed medication for the treatment of erectile dysfunction. 

It is also sometimes necessary to take tadalafil once a day, every day. You are permitted to attempt to engage in sexual activity at any time in between doses.

Depending on your health condition and the medications that you are currently taking, your doctor may advise you to take tadalafil less frequently or may prescribe a lower dose to be taken once a day instead.

Tadalafil Dosage

For treatment of erectile dysfunction, it’s recommended that you take not more than 20 mg of Tadalafil. 

For men who are planning to take the drug for the first time, it’s best to start with a low dose, such as 10 mg. You can increase your dosage (but not more than 20 mg per day) depending on how well your body reacts to the drug.

It’s also recommended that you take tadalafil an hour or at least 30 minutes prior to sexual activity. The effects of the drug will remain for approximately 24 to 36 hours after it’s taken.

Tadalafil is eliminated from the body partially through the kidneys in people with kidney disease. In the case of impaired kidney function, more of the medication may remain in your system for a longer period of time. Side effects are more likely to occur as a result. In some cases, your doctor may decide to reduce your dosage, have you take it less frequently, or even decide not to prescribe it for you at all. What you need depends on the severity of your kidney disease and whether or not you are receiving dialysis at this time.

See also Avanafil: How It Works, Side Effects and Benefits

Tadalafil Side Effects

Tadalafil Side Effects

This medication has been prescribed for you because your doctor has determined that the benefits to you are greater than the risk of side effects. Fortunately, however, most people who use this medication do not experience serious side effects.

If you have heart problems, there’s a good chance that you could experience one of these serious symptoms. To avoid these conditions, it’s important that you inform your doctor before and after you take tadalafil and engage in sexual activities.

Rarely, sudden decreased vision, including permanent blindness, in one or both eyes may occur. If this serious problem occurs, stop taking tadalafil and get medical help right away.

It is possible to experience a sudden decrease or loss of hearing, which may be accompanied by ringing in the ears and dizziness. If you experience any of these side effects, stop taking tadalafil and seek medical attention immediately. 

If you experience a painful or prolonged erection that lasts for more than 4 hours, discontinue use of this medication and seek medical attention immediately, otherwise permanent problems may result. 

It is extremely rare for this medication to cause a life-threatening allergic reaction. However, seek medical attention immediately if you experience any of the symptoms of a serious allergic reaction, which include: rash, itching/swelling (especially of the face, tongue, or throat), severe dizziness, or difficulty breathing.

Tadalafil Drug Interactions

Interactions between drugs can have unexpected and potentially dangerous consequences. Keeping track of all the products you use (including prescription and nonprescription medications, herbal products, and supplements) and sharing it with your doctor and pharmacist is highly recommended.

When used in conjunction with nitrates, tadalafil can cause a significant drop in blood pressure, which can result in dizziness, fainting, and, in rare cases, heart attack or stroke.

If you take tadalafil, or another PDE5 inhibitor like sildenafil, then you may want to consider your options carefully. These are some of the drugs that you should not use, or should only use under strict medical supervision: drugs to treat angina, nitrates, blood pressure drugs, recreational drugs, and any drug containing amyl or butyl nitrate.

If you are also taking an alpha blocker (such as doxazosin, tamsulosin), your blood pressure could drop too low which can cause dizziness and fainting.

There are other medications that may affect how tadalafil works. For example, certain HIV protease inhibitors (boceprevir, telaprevir) and azole antifungals (ketoconazole) can potentially affect how tadalafil works.

Other Things To Avoid

Grapefruit juice and grapefruit products should not be consumed with Cialis. As mentioned in the package insert for Cialis, grapefruit and grapefruit juice may interfere with the effectiveness of tadalafil.

Alcohol should also be avoided, as it can cause a drop in your blood pressure when used in conjunction with Tadalafil.

Tadalafil Vs Viagra

Tadalafil Vs Viagra

Both Viagra and Cialis are PDE-5 inhibitors. They cause the smooth muscles in the blood vessels that supply the penis to relax. This relaxation increases blood flow, which aids in obtaining an erection. However, the active ingredients in Viagra and Cialis are distinct. Sildenafil citrate is the PDE-5 inhibitor found in Viagra, whereas tadalafil citrate is found in Cialis.

Some men may be more sensitive to one active ingredient than another. However, because both sildenafil and tadalafil work through the same mechanism, you should never take the two medications at the same time. You should also avoid taking more than one Viagra or Cialis pill at a time. Both drugs require a sexual stimulus in order to be effective. Neither Viagra nor Cialis are capable of causing an erection on their own.

The most significant distinction between Viagra and Cialis is the length of time that their effects last. In most cases, Viagra is effective for 4 to 6 hours, giving you ample time to have sex on multiple occasions if you so desire. Cialis, on the other hand, is known to allow you to have erections for up to 36 hours after taking a tablet of it. Cialis has a half-life of up to 36 hours; however, this does not imply that you will have an erection at any point during that time; rather, it should only occur when you are sexually stimulated. Cialis has by far the longest duration of action of any erectile dysfunction medication currently available on the market.

Summary

Tadalafil is a drug that is well tolerated, with the most common side effects being headaches and flushing of the skin. There is a slight chance of developing priapism, but this is a rare side effect.

Tadalafil has a duration of action of up to 36 hours, and it should not be used in conjunction with nitrates or alpha blockers. You should always talk to your doctor before taking Tadalafil, especially if you have a medical condition or are taking medication.

The good news is that, for many men, Tadalafil is a safe and effective treatment for erectile dysfunction.

Frequently Asked Questions

How Long Does Tadalafil Last?

The effects of tadalafil can last for up to 36 hours in the body, so it’s important to avoid taking more than one tablet in a 24-hour period. It’s also important to note that you must be sexually aroused in order to experience the effects of the ED tablet.

Will Tadalafil Affect Blood Pressure?

When taken orally, tadalafil works by widening blood vessels in the body, making it easier for blood to flow through them. As a result, the medication may be effective in lowering blood pressure.

Is Tadalafil Better Than Viagra?

Tadalafil and Viagra are both used to treat erectile dysfunction, with the primary difference being the length of time that tadalafil lasts in comparison to Viagra. Tadalafil can remain in the body for up to 36 hours, whereas Viagra can remain in the body for up to 5 hours.

See also Dapoxetine (Priligy): A New and Effective Treatment for Premature Ejaculation